Max S Wicha Selected Research

Aldehyde Dehydrogenase

1/2020	EMP2 Is a Novel Regulator of Stemness in Breast Cancer Cells.
1/2018	Heterogeneity of Human Breast Stem and Progenitor Cells as Revealed by Transcriptional Profiling.
1/2018	Transcriptional profiles of different states of cancer stem cells in triple-negative breast cancer.
1/2014	Breast cancer stem cells transition between epithelial and mesenchymal states reflective of their normal counterparts.
12/2012	HER2-associated radioresistance of breast cancer stem cells isolated from HER2-negative breast cancer cells.
3/2012	Role of microRNAs in the regulation of breast cancer stem cells.
1/2012	Expression of aldehyde dehydrogenase and CD133 defines ovarian cancer stem cells.
6/2011	Aldehyde dehydrogenase in combination with CD133 defines angiogenic ovarian cancer stem cells that portend poor patient survival.
12/2010	Endothelial cell-initiated signaling promotes the survival and self-renewal of cancer stem cells.
9/2010	Single-marker identification of head and neck squamous cell carcinoma cancer stem cells with aldehyde dehydrogenase.

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Max S Wicha Research Topics

Disease

89	Neoplasms (Cancer) 08/2022 - 04/2003
59	Breast Neoplasms (Breast Cancer) 01/2022 - 07/2004
26	Neoplasm Metastasis (Metastasis) 08/2021 - 01/2010
10	Triple Negative Breast Neoplasms 11/2021 - 01/2015
9	Carcinogenesis 01/2021 - 01/2009
8	Squamous Cell Carcinoma of Head and Neck 08/2021 - 09/2010
5	Circulating Neoplastic Cells 12/2020 - 12/2014
4	Melanoma (Melanoma, Malignant) 08/2022 - 01/2014
4	Hypoxia (Hypoxemia) 01/2020 - 02/2012
3	Disease Progression 01/2022 - 01/2019
3	Head and Neck Neoplasms (Head and Neck Cancer) 01/2020 - 01/2016
3	Ovarian Neoplasms (Ovarian Cancer) 01/2015 - 06/2011
2	Hepatocellular Carcinoma (Hepatoma) 12/2020 - 03/2015
2	Mucoepidermoid Carcinoma 01/2019 - 09/2015
2	Inflammation (Inflammations) 01/2019 - 10/2011
2	Lung Neoplasms (Lung Cancer) 01/2017 - 10/2013
2	Prostatic Neoplasms (Prostate Cancer) 02/2013 - 05/2012
1	Residual Neoplasm 08/2022
1	Infections 11/2021
1	COVID-19 11/2021
1	Acute Lung Injury 11/2021
1	Graft vs Host Disease (Graft-Versus-Host Disease) 11/2021
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 11/2021
1	Colitis 11/2021
1	Pancreatic Neoplasms (Pancreatic Cancer) 01/2021
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2020
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2020

Drug/Important Bio-Agent (IBA)

15	Aldehyde DehydrogenaseIBA 01/2020 - 11/2007
10	VaccinesIBA 08/2022 - 04/2012
9	Interleukin-6 (Interleukin 6)IBA 01/2018 - 10/2011
8	Phenobarbital (Luminal)FDA Link 01/2019 - 01/2009
7	Biomarkers (Surrogate Marker)IBA 11/2021 - 08/2010
7	CytokinesIBA 01/2019 - 01/2011
6	Trastuzumab (Herceptin)FDA Link 08/2016 - 08/2012
5	MicroRNAs (MicroRNA)IBA 01/2021 - 01/2012
5	Proteins (Proteins, Gene)FDA Link 01/2020 - 01/2007
5	AntigensIBA 11/2017 - 04/2012
4	Estrogen ReceptorsIBA 01/2022 - 07/2004
4	Biocompatible Materials (Biomaterials)IBA 01/2021 - 01/2019
4	RNA (Ribonucleic Acid)IBA 01/2020 - 01/2018
4	Small Interfering RNA (siRNA)IBA 01/2017 - 01/2013
4	CurcuminIBA 01/2016 - 08/2010
3	Estrogens (Estrogen)FDA Link 01/2022 - 04/2016
3	Biological ProductsIBA 11/2021 - 06/2007
3	Transcription Factors (Transcription Factor)IBA 01/2020 - 01/2005
3	graphene oxideIBA 01/2019 - 10/2013
3	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 01/2018 - 04/2013
3	sulforaphaneIBA 01/2017 - 05/2010
3	Angiogenesis InhibitorsIBA 04/2015 - 02/2012
3	Interleukin-8 (Interleukin 8)IBA 10/2011 - 02/2009
2	Paclitaxel (Taxol)FDA LinkGeneric 11/2021 - 01/2017
2	Immune Checkpoint InhibitorsIBA 11/2021 - 10/2018
2	reparixinIBA 11/2021 - 02/2010
2	IntegrinsIBA 08/2021 - 01/2020
2	AdipokinesIBA 01/2019 - 12/2015
2	tocilizumab (atlizumab)FDA Link 01/2018 - 11/2014
2	3- (4- ((4- chlorophenyl)sulfonyl)- 4- (2,5- difluorophenyl)cyclohexyl)propanoic acidIBA 01/2018 - 03/2013
2	AntibodiesIBA 11/2017 - 01/2016
2	ChemokinesIBA 09/2017 - 01/2015
2	Phosphotransferases (Kinase)IBA 08/2017 - 09/2013
2	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2017 - 01/2009
2	Docetaxel (Taxotere)FDA Link 01/2017 - 03/2013
2	Pharmaceutical PreparationsIBA 08/2016 - 04/2015
2	integrin-linked kinaseIBA 04/2016 - 06/2015
2	SuspensionsIBA 01/2016 - 01/2005
2	Bevacizumab (Avastin)FDA Link 04/2015 - 02/2012
2	LigandsIBA 03/2015 - 04/2013
2	InterleukinsIBA 11/2014 - 10/2011
2	AndrogensIBA 02/2013 - 05/2012
2	piperineIBA 09/2011 - 08/2010
2	Aldehyde Dehydrogenase 1 FamilyIBA 08/2011 - 04/2009
2	TensinsIBA 06/2009 - 01/2007
1	Peptides (Polypeptides)IBA 08/2022
1	IronIBA 01/2022
1	Succinic Acid (Succinate)IBA 11/2021
1	Cell-Free Nucleic AcidsIBA 12/2020
1	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 11/2020
1	NanovaccinesIBA 10/2020
1	Rimantadine FDA LinkGeneric 01/2020
1	Protein Isoforms (Isoforms)IBA 01/2020
1	Tumor Biomarkers (Tumor Markers)IBA 11/2019
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2019
1	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 01/2019
1	MI-773IBA 01/2019
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2019
1	Fish OilsIBA 01/2019
1	Matrix Metalloproteinases (MMPs)IBA 10/2018
1	proteinase InIBA 10/2018
1	Peptide Hydrolases (Proteases)FDA Link 10/2018

Therapy/Procedure

39	Therapeutics 01/2022 - 04/2003
11	Drug Therapy (Chemotherapy) 11/2021 - 06/2008
10	Immunotherapy 08/2022 - 04/2012
4	Radiotherapy 08/2021 - 10/2010
4	Lab-On-A-Chip Devices 12/2019 - 12/2014
3	Replantation 04/2015 - 05/2010
2	Investigational Therapies (Experimental Therapy) 10/2016 - 03/2013
2	Chemoprevention 09/2011 - 05/2010
2	Aftercare (After-Treatment) 08/2011 - 06/2011
1	Immunomodulation 01/2021
1	Role Playing (Playing, Role) 01/2019